Open AccessDCLK1 Is Detectable in Plasma of Patients with Barrett’s Esophagus and Esophageal Adenocarcinoma
Author(s) -
Joshua Whorton,
Sripathi M. Sureban,
Randal May,
Dongfeng Qu,
Stan Lightfoot,
Mohammad F. Madhoun,
Milton Johnson,
William M. Tierney,
John T. Maple,
Kenneth J. Vega,
Courtney W. Houchen
Publication year - 2014
Publication title -
digestive diseases and sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 124
eISSN - 1573-2568
pISSN - 0163-2116
DOI - 10.1007/s10620-014-3347-4
Subject(s) - barrett's esophagus , immunohistochemistry , esophagus , pathology , stromal cell , medicine , adenocarcinoma , western blot , biomarker , gastroenterology , cancer , biology , biochemistry , gene
Doublecortin-like kinase 1 (DCLK1), a putative tumor stem cell marker has been shown to be highly expressed in the stromal and epithelial compartments in colon and pancreatic cancer as well as Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC).