Clinicopathological Significance of Serum Fractalkine in Primary Biliary Cirrhosis | Zendy

Kenichi Harada | Zendy; Yuko Kakuda | Zendy; Minoru Nakamura | Zendy; Shinji Shimoda | Zendy; Yasuni Nakanuma | Zendy

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Clinicopathological Significance of Serum Fractalkine in Primary Biliary Cirrhosis

Author(s) -

Kenichi Harada,

Yuko Kakuda,

Minoru Nakamura,

Shinji Shimoda,

Yasuni Nakanuma

Publication year - 2013

Publication title -

digestive diseases and sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.14

H-Index - 124

eISSN - 1573-2568

pISSN - 0163-2116

DOI - 10.1007/s10620-013-2734-6

Subject(s) - primary biliary cirrhosis , gastroenterology , medicine , hepatology , ursodeoxycholic acid , liver biopsy , bile duct , cirrhosis , biliary cirrhosis , fibrosis , pathogenesis , biopsy , pathology , disease , autoimmune disease

Primary biliary cirrhosis (PBC), characterized by cholangitis and loss of intrahepatic small bile ducts, predominantly affects middle-aged females. We have reported that fractalkine expression associated with chronic inflammation is observed in the damaged bile ducts and periductal vessels of PBC patients, which is closely associated with chronic cholangitis.

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