Open AccessTenofovir Disoproxil Fumarate for Prevention of Vertical Transmission of Hepatitis B Virus Infection by Highly Viremic Pregnant Women: A Case Series
Author(s) -
Calvin Q. Pan,
Li-Jun Mi,
Chalermrat Bunchorntavakul,
Jeffrey Karsdon,
William Huang,
Gaurav Singhvi,
Marc G. Ghany,
K. Rajender Reddy
Publication year - 2012
Publication title -
digestive diseases and sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 124
eISSN - 1573-2568
pISSN - 0163-2116
DOI - 10.1007/s10620-012-2187-3
Subject(s) - medicine , hepatitis b virus , hbeag , gestational age , pregnancy , hepatitis b , obstetrics , transmission (telecommunications) , hepatology , fetus , hbsag , immunology , virus , biology , electrical engineering , genetics , engineering
Despite appropriate immunoprophylaxis, up to 10 % of infants born to highly viremic hepatitis B virus (HBV-DNA ≥ 7 log IU/mL) mothers are infected with HBV. Use of TDF to prevent vertical transmission (VT) by such mothers has not been evaluated.