Open AccessInappropriate Angiogenic Response as a Novel Mechanism of Duodenal Ulceration and Impaired Healing
Author(s) -
Xiaoming Deng,
Ximing Xiong,
Tetyana Khomenko,
Zsuzsanna Sandor,
Klára Ösapay,
Ganna Tolstanova,
Joseph Shiloach,
Longchuan Chen,
Judah Folkman,
Sándor Szabó
Publication year - 2011
Publication title -
digestive diseases and sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 124
eISSN - 1573-2568
pISSN - 0163-2116
DOI - 10.1007/s10620-011-1753-4
Subject(s) - angiostatin , endostatin , mmp2 , medicine , mmp9 , angiogenesis , wound healing , matrix metalloproteinase , gastroenterology , pathogenesis , vascular endothelial growth factor , vegf receptors , cancer , surgery , metastasis , downregulation and upregulation , biology , biochemistry , gene
Despite recent advances and better understanding of the etiology and the pathogenesis of gastrointestinal ulcer diseases, e.g., duodenal ulcer, the molecular events leading to ulcer development, delayed healing, and recurrence remain poorly elucidated.