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Mannan-binding Lectin (MBL) Polymorphism and Gastric Cancer Risk in Japanese Population
Author(s) -
Fangyu Wang,
Tomomitsu Tahara,
Tomiyasu Arisawa,
Tomoyuki Shibata,
Hiromi Yamashita,
Masakatsu Nakamura,
Daisuke Yoshioka,
Masaaki Okubo,
Naoko Maruyama,
Toshiaki Kamano,
Yoshio Kamiya,
Masahiko Nakamura,
Hiroshi Fujita,
Mitsuo Nagasaka,
Masami Iwata,
Kazuya Takahama,
Makoto Watanabe,
Hiroshi Nakano,
Ichiro Hirata
Publication year - 2008
Publication title -
digestive diseases and sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 124
eISSN - 1573-2568
pISSN - 0163-2116
DOI - 10.1007/s10620-008-0249-3
Subject(s) - genotype , odds ratio , gastroenterology , medicine , allele , helicobacter pylori , cancer , immunology , mannan binding lectin , population , exon , biology , oncology , genetics , gene , lectin , environmental health
Mannan-binding lectin (MBL) is believed to be an important constituent of the innate immune system. It has been reported that the codon 54 G/A polymorphism of exon-1 affects the MBL2 gene and alters its activity.

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