Open AccessRelationship between right and left ventricular diastolic dysfunction assessed by 2-dimensional speckle-tracking echocardiography in adults with repaired tetralogy of Fallot
Author(s) -
Makoto Miyake,
Rie Abe,
Hayato Matsutani,
Jiro Sakamoto,
Hirokazu Kondo,
Atsushi Iwakura,
Hiraku Doi,
Toshihiro Tamura
Publication year - 2020
Publication title -
the international journal of cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.726
H-Index - 58
eISSN - 1875-8312
pISSN - 1569-5794
DOI - 10.1007/s10554-020-02045-7
Subject(s) - medicine , tetralogy of fallot , cardiology , speckle tracking echocardiography , diastole , subclinical infection , cardiac imaging , heart failure , ejection fraction , heart disease , blood pressure
Several studies have reported a correlation between right ventricular (RV) and left ventricular (LV) systolic dysfunction in adults with repaired tetralogy of Fallot (TOF). However, data are lacking regarding the relationship between RV and LV diastolic dysfunction assessed by 2-dimensional speckle-tracking echocardiography. We studied 69 adults with repaired TOF (mean age 34 years, 61% male) who had been regularly followed up and had routinely undergone echocardiography. In addition to conventional echocardiography, global longitudinal strain (GLS) and early diastolic strain rate (SRe) of both ventricles were assessed using 2-dimensional speckle-tracking echocardiography. Results were compared with 30 age- and sex-matched controls. RV and LV GLS were decreased in TOF patients compared with controls (− 18.4 ± 3.3% vs. −23.5 ± 4.2%, p < 0.001 and − 16.0 ± 3.8% vs. −20.0 ± 3.0%, p < 0.001, respectively). RV and LV SRe were also decreased in TOF patients compared with controls (1.22 ± 0.34 sec − 1 vs. 1.47 ± 0.41 sec − 1 , p = 0.003 and 1.29 ± 0.42 sec − 1 vs. 1.63 ± 0.42 sec − 1 , p < 0.001, respectively). A correlation between RV and LV SRe was found in TOF patients (r = 0.43, p < 0.001) as well as between RV and LV GLS (r = 0.45, p < 0.001). Two-dimensional speckle-tracking echocardiography reveals subclinical RV and LV diastolic dysfunction in adults with repaired TOF. A correlation is observed between RV and LV diastolic dysfunction as well as between RV and LV systolic dysfunction.