Open AccessAssociations between daily aspirin use and cancer risk across strata of major cancer risk factors in two large U.S. cohorts
Author(s) -
Lauren M. Hurwitz,
Kara A. Michels,
Michael B. Cook,
Ruth M. Pfeiffer,
Britton Trabert
Publication year - 2020
Publication title -
ccc. cancer causes and control/ccc, cancer causes and control
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.073
H-Index - 134
eISSN - 1573-7225
pISSN - 0957-5243
DOI - 10.1007/s10552-020-01357-2
Subject(s) - medicine , aspirin , hazard ratio , endometrial cancer , body mass index , oncology , colorectal cancer , breast cancer , proportional hazards model , prostate cancer , cancer , confidence interval , ovarian cancer , gynecology , relative risk , risk factor
Daily aspirin use has been shown to reduce risk of colorectal, and possibly other, cancers, but it is unknown if these benefits are consistent across subgroups of people with differing cancer risk factors. We investigated whether age, body mass index (BMI), smoking status, physical inactivity, and family history of cancer modify the effect of daily aspirin use on colorectal, ovarian, breast, endometrial and aggressive prostate cancer risk.