Open AccessA comparison of complete pathologic response rates following neoadjuvant chemotherapy among South African breast cancer patients with and without concurrent HIV infection
Author(s) -
Sarah Nietz,
Daniel S. O’Neil,
Oluwatosin Ayeni,
Wenlong Carl Chen,
Maureen Joffe,
Judith S. Jacobson,
Alfred I. Neugut,
Paul Ruff,
Witness Mapanga,
Ines Buccimazza,
Upasana Singh,
Sharon Čačala,
Laura Stopforth,
Boitumelo Phakathi,
Tobias Chirwa,
Herbert Cubasch
Publication year - 2020
Publication title -
breast cancer research and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.908
H-Index - 154
eISSN - 1573-7217
pISSN - 0167-6806
DOI - 10.1007/s10549-020-05889-8
Subject(s) - medicine , breast cancer , odds ratio , confidence interval , logistic regression , chemotherapy , cohort , oncology , cancer , stage (stratigraphy) , gastroenterology , surgery , paleontology , biology
Among patients diagnosed with breast cancer (BC), women also living with HIV (WLWH) have worse survival than women without HIV. Chronic HIV infection may interfere with the effectiveness of BC treatment, contributing to this disparity. We attempted to determine the impact of HIV infection on response to neoadjuvant chemotherapy (NACT) among South African women with BC.