Open AccessDetection of breast cancer stem cell gene mutations in circulating free DNA during the evolution of metastases
Author(s) -
Zhe Bin Liu,
Nader E. Ezzedine,
Agda Karina Eterovic,
Joe Ensor,
Helen J. Huang,
Joan Albanell,
Dong Soon Choi,
Ana Lluch,
Yi Liu,
Federico Rojo,
Helen Wong,
Eduardo Martínez-Dueñas,
Ángel Guerrero-Zotano,
Zhi Min Shao,
Jorge Darcourt,
Gordon B. Mills,
Bhuvanesh Dave,
Jenny C. Chang
Publication year - 2019
Publication title -
breast cancer research and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.908
H-Index - 154
eISSN - 1573-7217
pISSN - 0167-6806
DOI - 10.1007/s10549-019-05374-x
Subject(s) - digital polymerase chain reaction , breast cancer , mutation , biology , cancer research , stem cell , myeloid leukemia , cancer , leukemia , polymerase chain reaction , oncology , gene , medicine , genetics
Limited knowledge exists on the detection of breast cancer stem cell (BCSC)-related mutations in circulating free DNA (cfDNA) from patients with advanced cancers. Identification of new cancer biomarkers may allow for earlier detection of disease progression and treatment strategy modifications.