Open AccessEvaluation of radiation-induced cardiac toxicity in breast cancer patients treated with Trastuzumab-based chemotherapy
Author(s) -
Mohamed Abouegylah,
Lior Z. Braunstein,
Mohamed A. Alm El-Din,
Andrzej Niemierko,
Laura Salama,
M. Elebrashi,
Samantha K. Edgington,
Kyla Remillard,
Brian Napolitano,
George E. Naoum,
Hoda E. Sayegh,
Tessa C. Gillespie,
Mohamed Farouk,
Abdelsalam Ismail,
Alphonse G. Taghian
Publication year - 2018
Publication title -
breast cancer research and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.908
H-Index - 154
eISSN - 1573-7217
pISSN - 0167-6806
DOI - 10.1007/s10549-018-5053-y
Subject(s) - trastuzumab , cardiac toxicity , medicine , breast cancer , oncology , chemotherapy , toxicity , radiation therapy , cancer
Patients with Her2-positive breast cancer treated with trastuzumab have higher rates of cardiotoxicity (CT). Left-breast radiation might increase the risk for CT from cardiac exposure to radiation. The goal of our study is to evaluate the contribution of radiotherapy (RT) in the development of CT in breast cancer patients receiving trastuzumab.