Premium
Voice disorders in children with classic galactosemia
Author(s) -
Potter Nancy L.
Publication year - 2011
Publication title -
journal of inherited metabolic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 102
eISSN - 1573-2665
pISSN - 0141-8955
DOI - 10.1007/s10545-010-9213-4
Subject(s) - dysarthria , galactosemia , audiology , phonation , medicine , voice onset time , psychology , pediatrics , neuroscience , biochemistry , chemistry , perception , galactose
Children with classic galactosemia are at risk for motor speech disorders resulting from disruptions in motor planning and programming (childhood apraxia of speech or CAS) or motor execution (dysarthria). In the present study of 33 children with classic galactosemia, 21% were diagnosed with CAS, 3% with ataxic dysarthria, and 3% with mixed CAS‐dysarthria. Voice disorders due to laryngeal insufficiency were common in children with dysarthria and co‐occurred with CAS. Most (58%) of the children with classic galactosemia had decreased respiratory‐phonatory support for speech, and 33% had disturbed vocal quality that was indicative of cerebellar dysfunction. Three children, two diagnosed with CAS and one not diagnosed with a motor speech disorder, had vocal tremors. Treatment of voice dysfunction in neurogenic speech disorders is discussed.