Premium
Copper concentration of liver tissue under long‐term copper‐histidine therapy in a patient with Menkes disease
Author(s) -
Kroepfl T.,
Mair E.,
Deutsch J.,
BrunnerKrainz M.,
Paschke E.,
Plecko B.
Publication year - 2006
Publication title -
journal of inherited metabolic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 102
eISSN - 1573-2665
pISSN - 0141-8955
DOI - 10.1007/s10545-006-0312-1
Subject(s) - menkes disease , copper , histidine , cirrhosis , copper metabolism , medicine , chemistry , endocrinology , gastroenterology , biochemistry , amino acid , organic chemistry
Summary Copper‐histidine is the treatment of choice in Menkes disease but bears the potential risk of copper overload and induced liver cirrhosis. We report normal copper concentrations of liver tissue over an 8‐year treatment period with copper‐histidine.