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Principles of therapeutic liver repopulation
Author(s) -
Grompe Markus
Publication year - 2006
Publication title -
journal of inherited metabolic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 102
eISSN - 1573-2665
pISSN - 0141-8955
DOI - 10.1007/s10545-006-0311-2
Subject(s) - repopulation , human genetics , transplantation , biology , liver metabolism , liver transplantation , medicine , cancer research , bioinformatics , stem cell , genetics , endocrinology , haematopoiesis , gene
Summary Liver repopulation by transplanted hepatocytes is a promising approach for many inborn errors of metabolism. In this review, examples of liver repopulation in animals and the implications of these models for clinical cell transplantation will be discussed.