
Longitudinal sensitivity to change of MRI-based muscle cross-sectional area versus isometric strength analysis in osteoarthritic knees with and without structural progression: pilot data from the Osteoarthritis Initiative
Author(s) -
Torben Dannhauer,
M. Sattler,
W. Wirth,
David J. Hunter,
C. Kent Kwoh,
Felix Eckstein
Publication year - 2013
Publication title -
magma
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.585
H-Index - 62
eISSN - 1352-8661
pISSN - 0968-5243
DOI - 10.1007/s10334-013-0418-z
Subject(s) - isometric exercise , osteoarthritis , medicine , magnetic resonance imaging , thigh , knee joint , physical medicine and rehabilitation , anatomy , physical therapy , radiology , surgery , pathology , alternative medicine
Biomechanical measurement of muscle strength represents established technology in evaluating limb function. Yet, analysis of longitudinal change suffers from relatively large between-measurement variability. Here, we determine the sensitivity to change of magnetic resonance imaging (MRI)-based measurement of thigh muscle anatomical cross sectional areas (ACSAs) versus isometric strength in limbs with and without structural progressive knee osteoarthritis (KOA), with focus on the quadriceps.