Role of intrarenal (pro)renin receptor in ischemic acute kidney injury in rats | Zendy

Masafumi Ono | Zendy; Yukitoshi Sakao | Zendy; Takayuki Tsuji | Zendy; Naro Ohashi | Zendy; Hideo Yasuda | Zendy; Akira Nishiyama | Zendy; Yoshihide Fujigaki | Zendy; Akihiko Kato | Zendy

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Role of intrarenal (pro)renin receptor in ischemic acute kidney injury in rats

Author(s) -

Masafumi Ono,

Yukitoshi Sakao,

Takayuki Tsuji,

Naro Ohashi,

Hideo Yasuda,

Akira Nishiyama,

Yoshihide Fujigaki,

Akihiko Kato

Publication year - 2014

Publication title -

clinical and experimental nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.765

H-Index - 50

eISSN - 1437-7799

pISSN - 1342-1751

DOI - 10.1007/s10157-014-0979-9

Subject(s) - renin–angiotensin system , medicine , endocrinology , kidney , mapk/erk pathway , angiotensin ii receptor type 1 , renal ischemia , ischemia , angiotensin ii , olmesartan , receptor , phosphorylation , nephrology , chemistry , reperfusion injury , biochemistry , blood pressure

(Pro)renin receptor [(P)RR], a trans-membrane receptor for renin and prorenin, is involved in the local activation of renin-angiotensin system (RAS) in the kidney. However, it remains to be determined whether (P)RR plays a role in the development of ischemic acute kidney injury (AKI).

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