High-resolution genotyping of Aspergillus fumigatus isolates recovered from chronically colonised patients with cystic fibrosis
Author(s) -
L.-M.-E. Vanhee,
F. Symoens,
JeanPhilippe Bouchara,
H.-J. Nelis,
Tom Coenye
Publication year - 2008
Publication title -
european journal of clinical microbiology and infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.154
H-Index - 106
eISSN - 1435-4373
pISSN - 0934-9723
DOI - 10.1007/s10096-008-0527-1
Subject(s) - genotyping , aspergillus fumigatus , colonisation , genotype , cystic fibrosis , typing , microbiology and biotechnology , biology , medical microbiology , microsatellite , aspergillus , allele , genetics , colonization , gene
A series of 256 Aspergillus fumigatus isolates, recovered from eight patients with cystic fibrosis (CF), were genotyped using microsatellite-based typing. Only a limited number of genotypes were shared between patients and co-colonisation with multiple strains was indicated for all patients. Additionally, some genotypes were isolated recurrently, indicating that they are capable of prolonged colonisation.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom