Open AccessRescue therapies for seizure emergencies: current and future landscape
Author(s) -
Debopam Samanta
Publication year - 2021
Publication title -
neurological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.767
H-Index - 71
eISSN - 1590-3478
pISSN - 1590-1874
DOI - 10.1007/s10072-021-05468-9
Subject(s) - medicine , midazolam , status epilepticus , intensive care medicine , levetiracetam , lorazepam , epilepsy , anesthesia , psychiatry , sedation
Seizure emergencies-status epilepticus and seizure clusters-require rapid evaluation and treatment. Several consensus-based guidelines support a prompt use of intravenous benzodiazepines as the first-line therapy in seizure emergencies. However, most seizure emergencies start outside the hospital settings. Until recently, approved prehospital rescue therapies were limited to rectal diazepam and buccal midazolam (Europe only).