Open AccessPlatform technologies for regenerative endodontics from multifunctional biomaterials to tooth-on-a-chip strategies
Author(s) -
Diana Gabriela Soares,
Ester Alves Ferreira Bordini,
W. Benton Swanson,
Carlos Alberto de Souza Costa,
Marco C. Bottino
Publication year - 2021
Publication title -
clinical oral investigations
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.088
H-Index - 82
eISSN - 1436-3771
pISSN - 1432-6981
DOI - 10.1007/s00784-021-04013-4
Subject(s) - endodontics , pulp (tooth) , dentistry , tissue engineering , regenerative medicine , regeneration (biology) , limiting , biomaterial , medicine , biomedical engineering , engineering , stem cell , biology , mechanical engineering , microbiology and biotechnology , genetics
The aim of this review is to highlight recent progress in the field of biomaterials-mediated dental pulp tissue engineering. Specifically, we aim to underscore the critical design criteria of biomaterial platforms that are advantageous for pulp tissue engineering, discuss models for preclinical evaluation, and present new and innovative multifunctional strategies that hold promise for clinical translation.