Open AccessThe role of M1 and M2 macrophage polarization in progression of medication-related osteonecrosis of the jaw
Author(s) -
Polytimi Paschalidi,
Ioannis Gkouveris,
Akrivoula Soundia,
Evangelos Kalfarentzos,
Emmanouil Vardas,
Maria Georgaki,
George Kostakis,
Boban M. Erović,
Sotirios Tetradis,
Christos Perisanidis,
Nikolaos G. Nikitakis
Publication year - 2020
Publication title -
clinical oral investigations
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.088
H-Index - 82
eISSN - 1436-3771
pISSN - 1432-6981
DOI - 10.1007/s00784-020-03602-z
Subject(s) - cd68 , denosumab , osteonecrosis of the jaw , macrophage polarization , medicine , macrophage , m2 macrophage , immunofluorescence , pathology , cancer research , immunohistochemistry , immunology , chemistry , antibody , osteoporosis , in vitro , biochemistry , bisphosphonate
The aim of this study was to investigate the relationship between M1 and M2 macrophage polarization and clinical stage in patients with medication-related osteonecrosis of the jaw (MRONJ) who underwent treatment with bisphosphonates or denosumab.