Open AccessDDR2, a discoidin domain receptor, is a marker of periosteal osteoblast and osteoblast progenitors
Author(s) -
Huiwen Yang,
Lei Sun,
Wenqian Cai,
Jingkai Gu,
Dacai Xu,
Arjun Deb,
Jinzhu Duan
Publication year - 2020
Publication title -
journal of bone and mineral metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.721
H-Index - 74
eISSN - 1435-5604
pISSN - 0914-8779
DOI - 10.1007/s00774-020-01108-y
Subject(s) - periosteum , osteoblast , progenitor cell , chemistry , microbiology and biotechnology , colocalization , fibroblast , anatomy , pathology , biology , stem cell , medicine , biochemistry , in vitro
The periosteum has a bilayered structure that surrounds cortical bone. The outer layer is rich in connective tissue and fibroblasts, while the inner layer in contact with the cortical surface of the bone predominantly consists of osteoblasts and osteoblast progenitors. The identification of cell-specific surface markers of the bilayered structure of the periosteum is important for the purpose of tissue regeneration.