Low metabolic activity in primary gastric adenocarcinoma is associated with resistance to chemoradiation and the presence of signet ring cells | Zendy

Kazuto Harada | Zendy; Madhavi Patnana | Zendy; Xuemei Wang | Zendy; Masaaki Iwatsuki | Zendy; Mariela A. Blum Murphy | Zendy; Meina Zhao | Zendy; Prajnan Das | Zendy; Bruce D. Minsky | Zendy; Brian Weston | Zendy; Jeffrey H. Lee | Zendy; Manoop S. Bhutani | Zendy; Jeannelyn S. Estrella | Zendy; Namita Shanbhag | Zendy; Naruhiko Ikoma | Zendy; Brian D. Badgwell | Zendy; Jaffer A. Ajani | Zendy

Open Access

Low metabolic activity in primary gastric adenocarcinoma is associated with resistance to chemoradiation and the presence of signet ring cells

Author(s) -

Kazuto Harada,

Madhavi Patnana,

Xuemei Wang,

Masaaki Iwatsuki,

Mariela A. Blum Murphy,

Meina Zhao,

Prajnan Das,

Bruce D. Minsky,

Brian Weston,

Jeffrey H. Lee,

Manoop S. Bhutani,

Jeannelyn S. Estrella,

Namita Shanbhag,

Naruhiko Ikoma,

Brian D. Badgwell,

Jaffer A. Ajani

Publication year - 2020

Publication title -

surgery today

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.655

H-Index - 63

eISSN - 1436-2813

pISSN - 0941-1291

DOI - 10.1007/s00595-020-02018-2

Subject(s) - medicine , signet ring cell , surgical oncology , adenocarcinoma , signet ring cell carcinoma , oncology , gastroenterology , cancer , general surgery

Preoperative chemoradiation is a potential treatment option for localized gastric adenocarcinoma (GAC). Currently, the response to chemoradiation cannot be predicted. We analyzed the pretreatment maximum standardized uptake value (SUV max ) and total lesion glycolysis (TLG) on positron emission tomography/computed tomography as potential predictors of the response to chemoradiation.

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