Open AccessSupragastric belching in Japan: lower prevalence and relevance for management of gastroesophageal reflux disease compared to United Kingdom
Author(s) -
Akinari Sawada,
Hideaki Itami,
Kenichiro Nakagawa,
Shinji Hirano,
Hiroyuki Kitamura,
Rieko Nakata,
Shingo Takashima,
Yuina Abe,
Masahiro Saito,
Etsuro Yazaki,
Osamu Kawamura,
Fumio Tanaka,
Toshihisa Takeuchi,
Tomoyuki Koike,
Atsushi Masamune,
Yasuhiro Fujiwara,
Kazuhide Higuchi,
Daniel Sifrim
Publication year - 2020
Publication title -
journal of gastroenterology
Language(s) - English
Resource type - Journals
eISSN - 1435-5922
pISSN - 0944-1174
DOI - 10.1007/s00535-020-01720-9
Subject(s) - medicine , reflux , gerd , gastroenterology , disease , odds ratio , hepatology , refractory (planetary science) , logistic regression , clinical significance , physics , astrobiology
Supragastric belching (SGB) may play a role in the pathophysiology of proton pump inhibitors (PPIs)-refractoriness in gastroesophageal reflux disease (GERD). SGB may be present in up to 40% of reflux symptoms in PPI-refractory GERD. Most reports on SGB have come from Western countries, and little is known about the prevalence and relevance of SGB in Asian refractory GERD patients. This study aimed at comparing the role of SGB in GERD patients in Japan and the UK.