Epitope peptides of Helicobacter pylori CagA antibodies from sera by whole-peptide mapping | Zendy

Shamshul Ansari | Zendy; Junko Akada | Zendy; Yuichi Matsuo | Zendy; Seiji Shiota | Zendy; Yoko Kudo | Zendy; Tadayoshi Okimoto | Zendy; Kazunari Murakami | Zendy; Yoshio Yamaoka | Zendy

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Epitope peptides of Helicobacter pylori CagA antibodies from sera by whole-peptide mapping

Author(s) -

Shamshul Ansari,

Junko Akada,

Yuichi Matsuo,

Seiji Shiota,

Yoko Kudo,

Tadayoshi Okimoto,

Kazunari Murakami,

Yoshio Yamaoka

Publication year - 2019

Publication title -

journal of gastroenterology

Language(s) - English

Resource type - Journals

eISSN - 1435-5922

pISSN - 0944-1174

DOI - 10.1007/s00535-019-01584-8

Subject(s) - caga , epitope , peptide , helicobacter pylori , immunogenicity , antibody , amino acid , microbiology and biotechnology , peptide sequence , biology , biochemistry , chemistry , immunology , genetics , gene , virulence

Helicobacter pylori CagA has been found to be immuno-dominant protein and utilized for the diagnosis of the infection with cagA-positive strains. It is important to characterize the peptide epitopes capable of detecting serum anti-CagA antibodies to understand CagA immunogenicity.

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