Open AccessStatin use and pancreatic cancer risk in two prospective cohort studies
Author(s) -
Tsuyoshi Hamada,
Natalia Khalaf,
Chen Yuan,
Ana Babić,
Vicente Morales-Oyarvide,
Zhi Rong Qian,
Jonathan A. Nowak,
Kimmie Ng,
Peter Kraft,
Douglas A. Rubinson,
Meir J. Stampfer,
Edward Giovannucci,
Charles S. Fuchs,
Shuji Ogino,
Brian M. Wolpin
Publication year - 2018
Publication title -
journal of gastroenterology
Language(s) - English
Resource type - Journals
eISSN - 1435-5922
pISSN - 0944-1174
DOI - 10.1007/s00535-018-1430-x
Subject(s) - medicine , prospective cohort study , surgical oncology , hepatology , abdominal surgery , pancreatic cancer , colorectal surgery , cancer , statin , cohort study , oncology , general surgery
Statins, 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, are common lipid-lowering agents and may reduce the risk of several cancer types including pancreatic cancer. However, the association between statin use and pancreatic cancer risk has not been fully evaluated in prospective studies.