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Living‐donor liver transplantation for Caroli's disease with intrahepatic adenocarcinoma
Author(s) -
Takatsuki Mitsuhisa,
Uemoto Shinji,
Inomata Yukihiro,
Egawa Hiroto,
Kiuchi Tetsuya,
Hayashi Michihiro,
Ueda Mikiko,
Tanaka Koichi
Publication year - 2001
Publication title -
journal of hepato‐biliary‐pancreatic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 0944-1166
DOI - 10.1007/s005340170030
Subject(s) - medicine , intrahepatic bile ducts , liver transplantation , intrahepatic cholangiocarcinoma , papillary adenocarcinoma , papillary tumor , transplantation , bile duct , adenocarcinoma , pathological , gastroenterology , pathology , cancer
A 36‐year‐old woman who had Caroli's disease with refractory cholangitis and complicated intrahepatic cholangiocarcinoma was successfully treated with living‐donor liver transplantation. Preoperative computed tomography and ultrasonography showed a small nodule in the dilated intrahepatic bile duct. In the resected liver specimen, a small papillary tumor was located in the dilated intrahepatic bile duct of the right lobe. The pathological finding revealed a well differentiated papillary adenocarcinoma without invasion to the parenchyma. The patient is currently doing well 2.5 years after transplantation, with no signs of recurrence of the disease. For Caroli's disease, we believe we can achieve good results with liver transplantation, not only for cholangitis but also for the carcinoma when it is localized in the liver and the patient is carefully followed up.