Premium
Extrahepatic large hepatocellular carcinoma with peritoneal dissemination: multimodal treatment, including four surgical operations
Author(s) -
Tanaka Akira,
Takeda Ryoji,
Yamamoto Hidekazu,
Utsunomiya Hirohito,
Okamura Ryuji,
Kataoka Masato,
Mukaihara Sumio,
Yamaoka Yoshio
Publication year - 2000
Publication title -
journal of hepato‐biliary‐pancreatic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 0944-1166
DOI - 10.1007/s005340070060
Subject(s) - medicine , hepatocellular carcinoma , arterial embolization , multimodal therapy , chemotherapy , embolization , mesentery , surgery , hyperthermia , radiology
We report a patient with extrahepatically growing large hepatocellular carcinoma (HCC) associated with dis‐seminated intraabdominal tumor and spontaneous tumor bleeding who was treated with four operations, transcatheter arterial embolization, systemic chemotherapy, and hyperthermia. It took 12 months for the multimodal treatment to normalize the alpha‐fetoprotein (AFP) level, and remission continued for 6 months. We performed the fourth surgical treatment for a recurrent abdominal tumor involving the small intestine and mesentery, but the patient died 26 months after the first admission. Multimodal treatment, including repeat surgical treatments, for such advanced HCC should be encouraged, to prolong life and to maintain quality of life.