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Intrahepatic cholangiocarcinoma in Taiwan
Author(s) -
Chen MiinFu,
Jan YiYin,
Jeng LongBin,
Hwang TsannLong,
Wang ChiaSiu,
Chen ShinCheh,
Chao TzuChieh,
Chen HanMing,
Lee WeiChen,
Yeh TaSen,
Lo YunFan
Publication year - 1999
Publication title -
journal of hepato‐biliary‐pancreatic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 0944-1166
DOI - 10.1007/s005340050096
Subject(s) - hepatolithiasis , medicine , concomitant , bile duct , intrahepatic bile ducts , gastroenterology , mortality rate , hepatectomy , resection , surgery
We report our experience of the surgical treatment of intrahepatic cholangiocarcinoma (ICC) in Taiwanese patients. A tota1 of 162 patients with histologically proven ICC were treated of whom 106 (65.4%) had associated hepatolithiasis. Patients with hepatolithiasis were in earlier stages than those without hepatolithiasis. Two‐thirds of the patients with hepatolithiasis presented with acute cholangitis, and two‐thirds of those without hepatolithiasis presented with hepatomegaly. The rate of hepatic resection was 29.6% (48 of 162), and these rates were 31.1% and 26.8% for the patients with and without hepatolithiasis, respectively. Ninety‐three percent of the patients with hepatolithiasis underwent common bile duct exploration, compared with 18% of those without hepatolithiasis. The surgical mortality rates were 3.7% (6/162), for all patients, and 3.8% and 3.6% for patients with and without hepatolithiasis, respectively. The morbidity rate was much higher in the patients with hepatolithiasis (37.7% vs 16.1%). The 1‐, 3‐, and 5‐year survival rates were 35.5%, 20.5%, and 16.5% in the patients with hepatolithiasis and 27.2%, 8.8%, and 7.8% in those without hepatolithiasis. Concomitant hepatolithiasis prevented precise diagnosis preoperatively and precipitated biliary sepsis, which affected resectability and increased postoperative morbidity. Hepatolithiasis per se did not influence long‐term survival.