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Resection of hepatic metastases of colorectal carcinoma: 20 years' experience
Author(s) -
Nakamura Satoshi,
Suzuki Shohachi,
Konno Hiroyuki
Publication year - 1999
Publication title -
journal of hepato‐biliary‐pancreatic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 0944-1166
DOI - 10.1007/s005340050079
Subject(s) - medicine , hepatectomy , lymphadenectomy , colorectal cancer , metastasis , dissection (medical) , carcinoma , survival rate , gastroenterology , surgery , lymph node , oncology , resection , cancer
We analyzed the results and the prognostic factors influencing survival in 79 patients with metastases of colorectal carcinoma who underwent hepatectomy at our hospital in the 20‐year period 1978—1998. The 5‐ and 10‐year survival rates were 49% and 33%, respectively. Repeat hepatectomy was done 29 times in 24 patients with relapse of liver tumors. The 3‐ and 5‐year survival rates after repeat hepatectomy were 58% and 14%, respectively. The distribution of and number of tumors in the liver, the disease‐free interval from initial to second hepatectomy, and the presence of extrahepatic disease were significantly associated with survival ( P < 0.01). Seven of 43 patients who underwent hilar node dissection had metastasis and 2 of them survived for more than 5 years. Repeat hepatectomy and hilar lymphadenectomy may be effective in prolonging the sur‐vival of selected patients with hepatic metastasis. We also discuss prognostic factors after extensive surgery for hepatic metastases of colorectal carcinoma.