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Ultrasonography‐guided hepatic tumor resection using a real‐time virtual sonography with indocyanine green navigation (with videos)
Author(s) -
Kasuya Kazuhiko,
Sugimoto Katsutoshi,
Kyo Bunsoh,
Nagakawa Yuichi,
Ikeda Takahisa,
Mori Yasuharu,
Wada Tatehiko,
Suzuki Minako,
Nagai Takeshi,
Itoi Takao,
Shimazu Motohide,
Aoki Tatsuya,
Tsuchida Akihiko
Publication year - 2011
Publication title -
journal of hepato‐biliary‐pancreatic sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 1868-6974
DOI - 10.1007/s00534-010-0356-3
Subject(s) - indocyanine green , medicine , magnetic resonance imaging , radiology , ultrasonography , pathological , resection , lesion , nuclear medicine , pathology , surgery
Abstract Purpose For hepatic tumors that cannot be identified on routine ultrasonography (US), we marked the target area using real‐time virtual sonography (RVS) with indocyanine green (ICG)–ethanol (1:100) during surgery, and performed hepatic resection while observing the fluorescence. Experiment An ICG–ethanol mixture locally injected into mouse liver was retained in the same area for more than 4 h. The same mixture locally injected into pig liver at a depth of 3 cm could be observed using an infrared camera. Case An ICG–ethanol mixture (500 μl) was locally injected under RVS guidance into a metastatic hepatic tumor that was visible only on magnetic resonance imaging (MRI), and hepatic resection was performed while Photodynamic Eye (PDE) images were being observed. The metastatic lesion (3 mm in diameter in a pathological specimen) could be successfully resected. Conclusion This method was useful for resecting US‐invisible hepatic tumors.