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Donor quality of life after living donor liver transplantation: a prospective study
Author(s) -
Togashi Junichi,
Sugawara Yasuhiko,
Tamura Sumihito,
Yamashiki Noriyo,
Kaneko Junichi,
Aoki Taku,
Hasegawa Kiyoshi,
Beck Yoshifumi,
Makuuchi Masatoshi,
Kokudo Norihiro
Publication year - 2011
Publication title -
journal of hepato‐biliary‐pancreatic sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 1868-6974
DOI - 10.1007/s00534-010-0340-y
Subject(s) - medicine , liver transplantation , quality of life (healthcare) , prospective cohort study , living donor liver transplantation , transplantation , population , surgery , gerontology , environmental health , nursing
Background/purpose It is important to determine the health‐related quality of life of live donors in liver transplantation. Materials and methods We reviewed 35 live liver donors and prospectively and longitudinally evaluated their health‐related quality for 1.5 years post‐surgery based on the Short Form‐36 version 2 questionnaire. Scores of the donors stratified by the clinical data were analyzed. The study was approved by the University of Tokyo Institutional Review Board (No. 1533). Results There was no donor mortality in the donor population studied. The percentage of major complications greater than Clavien's classification grade III was 8.6%. The physical component summary score decreased to 42.9 ( p < 0.01) at 3 months, but recovered within 6 months after the operation. The mental component summary scores did not change during the observation period. The stratification study revealed that age and postoperative complications remained significant factors among the high physical component summary scores 3 months after the operation. Conclusions The findings from this survey suggest that liver harvesting does not decrease the donor's quality of life during the 1.5 years following the surgery.