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Double primary liver cancer (intrahepatic cholangiocarcinoma and hepatocellular carcinoma) in a patient with hepatitis C virus‐related cirrhosis
Author(s) -
Inaba Keisuke,
Suzuki Shohachi,
Sakaguchi Takanori,
Kobayasi Yoshimasa,
Takehara Yasuo,
Miura Katsutoshi,
Baba Satoshi,
Nakamura Satoshi,
Konno Hiroyuki
Publication year - 2007
Publication title -
journal of hepato‐biliary‐pancreatic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 0944-1166
DOI - 10.1007/s00534-006-1134-0
Subject(s) - hepatocellular carcinoma , medicine , intrahepatic cholangiocarcinoma , cirrhosis , liver cancer , gastroenterology , hepatitis c virus , hepatectomy , transcatheter arterial chemoembolization , cancer , resection , virus , surgery , immunology
We herein report a rare case of double primary liver cancer, consisting of intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC). A 67‐year‐old Japanese man with hepatitis C virus‐related liver cirrhosis was diagnosed with multiple HCC in S7 and S8 of the liver. We performed a hepatic resection of S7 and S8. The liver tumors in S7 and S8 were pathologically diagnosed as HCC and ICC, respectively. Multiple recurrence of the HCC found 7 years after the surgery was successfully treated with transcatheter arterial chemoembolization. Subsequently, this patient has been doing well, without HCC recurrence. Double primary liver cancer is very rare, and only 21 resected cases have been reported, including that in our patient. We reviewed at all cases in the Japanese‐ and English‐language literature to investigate the clinicopathological features. Our literature review revealed that the present patient is the longest survivor among patients who have undergone hepatectomy for double primary liver cancer.