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Prognostic parameters for the prediction of acute gangrenous cholecystitis
Author(s) -
Aydin Cagatay,
Altaca Gülüm,
Berber Ibrahim,
Tekin Koray,
Kara Melih,
Titiz Izzet
Publication year - 2006
Publication title -
journal of hepato‐biliary‐pancreatic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 0944-1166
DOI - 10.1007/s00534-005-1042-8
Subject(s) - medicine , cholecystitis , diabetes mellitus , multivariate analysis , univariate analysis , acute cholecystitis , gangrene , white blood cell , cholecystectomy , surgery , gallbladder , endocrinology
Background/Purpose The aim of this study was to identify preoperative prognostic parameters for gangrenous cholecystitis to differentiate this subgroup of patients with acute cholecystitis in order to provide immediate surgical therapy. Methods The medical records of patients who had an emergency cholecystectomy with the diagnosis of acute cholecystitis between January 2002 and June 2005 were reviewed retrospectively. Univariate and multivariate analysis were performed on the data. Results Out of 203 individuals with the clinical diagnosis of acute cholecystitis, 21 (10.3%) patients had a histological diagnosis of gangrenous cholecystitis. Multivariate analysis demonstrated an independent association of male sex, diabetes mellitus and white blood cell (WBC) count with the development of acute gangrenous cholecystitis. Conclusions The risk for gangrenous cholecystitis is increased in male patients who have diabetes and a greater WBC count than 14900/mm 3 . Urgent surgical intervention should be considered for these patients because of the high morbidity and mortality rate of the condition.