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Carcinosarcoma of the extrahepatic bile duct
Author(s) -
Kadono Jun,
Hamada Nobuo,
Higashi Michiyo,
Ishizaki Naoki,
Nakamura Noboru,
Sakata Ryuzo
Publication year - 2005
Publication title -
journal of hepato‐biliary‐pancreatic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 0944-1166
DOI - 10.1007/s00534-005-0988-x
Subject(s) - carcinosarcoma , medicine , bile duct , percutaneous transhepatic cholangiography , calcification , common bile duct , lesion , radiology , cholangiography , intrahepatic bile ducts , dystrophic calcification , common hepatic duct , pathology , carcinoma , gastroenterology
Abstract A rare case of a carcinosarcoma of the extrahepatic bile duct demonstrating interesting features is described. A 75‐year‐old woman with a history of choledocholithotomy presented with acute obstructive suppurative cholangitis. Ultrasonography and computed tomography showed a thickened choledochal wall, with calcification. Percutaneous transhepatic and endoscopic retrograde cholangiography revealed a round filling defect accompanied by an irregular obstruction in the common bile duct. Carcinosarcoma was diagnosed from a protruding lesion in the common bile duct obtained by intraoperative frozen sectioning, and pylorus‐preserving pancreatoduodenectomy was performed. Histological examination by light microscopy showed a transition between the carcinomatous and sarcomatous components and positive immunoreactivity for epithelial markers in the sarcomatous component. The patient died of a local recurrence 2 years after the surgery. Polypoid growth and ossification in the tumor could be representative features of carcinosarcoma of the extrahepatic bile duct.