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Laparoscopic resection for nonfunctioning small glucagon‐producing tumor: report of a case and review of the literature
Author(s) -
Yada Kazuhiro,
Hirano Seitaro,
Himeno Yoshihisa,
Shibata Kohei,
Matsumoto Toshifumi,
Aramaki Masanori,
Kawano Katsunori,
Kitano Seigo
Publication year - 2003
Publication title -
journal of hepato‐biliary‐pancreatic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 0944-1166
DOI - 10.1007/s00534-002-0826-3
Subject(s) - medicine , chromogranin a , pancreas , glucagon , glucagonoma , pancreatic tumor , endocrine system , laparoscopy , abdominal ultrasonography , pancreatic mass , laparoscopic surgery , radiology , immunohistochemistry , hormone , ultrasonography , pancreatic cancer , cancer
Abstract Glucagonoma is a relatively rare type of pancreatic endocrine tumor, and is often well‐developed and malignant at detection. We report a case of nonfunctioning small glucagon‐producing tumor that was successfully resected by laparoscopic surgery. A 63‐year‐old woman was admitted to our hospital for further examination of a pancreatic tumor that had been detected incidentally. Hematological data and hormone concentrations were within normal ranges. Abdominal ultrasonography and computed tomography showed a small mass in the body of the pancreas. Laparoscopic distal pancreatectomy was done. Macroscopically, the resected tumor was a yellowish‐white, solid mass measuring 8 × 8 × 7 mm. The tumor cells showed positive immunohistochemical staining for chromogranin A and glucagon. The postoperative course was uneventful. To the best of our knowledge, this is the first report of laparoscopic surgery for a nonfunctioning small glucagon‐producung tumor. Because of recent improvements in laparoscopic surgery technique, use of this approach for resection of pancreatic benign small endocrine tumors will likely increase in the future.

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