Open Access
Prospective patient-reported symptom profiles associated with pediatric acute lymphoblastic leukemia relapse
Author(s) -
Austin L. Brown,
Kimberly P. Raghubar,
Olga A. Taylor,
M. Brooke Bernhardt,
Lisa S. Kahalley,
Wei Pan,
Philip J. Lupo,
Marilyn Hockenberry,
Michael E. Scheurer
Publication year - 2020
Publication title -
supportive care in cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.133
H-Index - 112
eISSN - 1433-7339
pISSN - 0941-4355
DOI - 10.1007/s00520-020-05773-7
Subject(s) - medicine , nausea , hazard ratio , confidence interval , proportional hazards model , prospective cohort study , incidence (geometry) , vomiting , pediatrics , physics , optics
Despite improvements in frontline pediatric acute lymphoblastic leukemia (ALL) treatment, relapse remains a concern. Research in adult cancer patients suggests that patient-reported symptoms may predict survival, but the relationship between symptoms and relapse for pediatric ALL has received little attention.