Open AccessMicrobiome-gut-brain axis in cancer treatment-related psychoneurological toxicities and symptoms: a systematic review
Author(s) -
Byron Chang Song,
Jinbing Bai
Publication year - 2020
Publication title -
supportive care in cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.133
H-Index - 112
eISSN - 1433-7339
pISSN - 0941-4355
DOI - 10.1007/s00520-020-05739-9
Subject(s) - medicine , lachnospiraceae , cancer , microbiome , gut flora , medline , nursing research , bioinformatics , pathology , immunology , biology , biochemistry , genetics , 16s ribosomal rna , bacteria , firmicutes
The microbiome-gut-brain (MGB) axis provides a dynamic model to understand associations between the gut microbiota and psychoneurological comorbidities. The role of the MGB axis in cancer treatment-related psychoneurological symptoms (PNS) remains unknown. The purpose of this study was to conduct a systematic review of the existing literature to identify the influence of the gut microbiota on cancer and cancer treatment-related PNS and toxicities mediated by the MGB axis.