Does MEST-C score predict outcomes in pediatric Henoch-Schönlein purpura nephritis? | Zendy

Adam Jimenez | Zendy; Ashton Chen | Zendy; JenJar Lin | Zendy; Andrew M. South | Zendy

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Does MEST-C score predict outcomes in pediatric Henoch-Schönlein purpura nephritis?

Author(s) -

Adam Jimenez,

Ashton Chen,

JenJar Lin,

Andrew M. South

Publication year - 2019

Publication title -

pediatric nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.831

H-Index - 107

eISSN - 1432-198X

pISSN - 0931-041X

DOI - 10.1007/s00467-019-04327-2

Subject(s) - medicine , proteinuria , renal function , kidney disease , nephrology , receiver operating characteristic , gastroenterology , nephropathy , logistic regression , cohort , creatinine , nephritis , renal biopsy , area under the curve , kidney , endocrinology , diabetes mellitus

Children with Henoch-Schönlein purpura nephritis (HSPN) have an increased risk of chronic kidney disease (CKD). Renal biopsy diagnostic of HSPN is graded using the International Study of Kidney Disease in Children criteria, which do not predict outcomes. The 2016 Oxford Classification's MEST-C scoring system predicts outcomes in adults with histologically identical IgA nephropathy, but evidence of its utility in pediatric HSPN is lacking. Our hypothesis was that MEST-C scores predict outcomes in children with HSPN.

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