Open AccessClinical characteristics and outcomes of SDHB-related pheochromocytoma and paraganglioma in children and adolescents
Author(s) -
Ivana Jochmanová,
April Melody T Abcede,
Ruby Jane S Guerrero,
Chandy Lou Malong,
Robert Wesley,
Thanh Huynh,
Melissa Gonzales,
Katherine I. Wolf,
Karel Pacák,
Marianne Knue,
Tamara Prodanov,
Naris Nilubol,
Leilani B. Mercado-Asis,
Constantine A. Stratakis
Publication year - 2020
Publication title -
journal of cancer research and clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.338
H-Index - 94
eISSN - 1432-1335
pISSN - 0171-5216
DOI - 10.1007/s00432-020-03138-5
Subject(s) - sdhb , medicine , pheochromocytoma , paraganglioma , hematology , germline mutation , disease , abdominal pain , pediatrics , metastasis , oncology , pathology , cancer , mutation , gene , biochemistry , chemistry
Pheochromocytomas/paragangliomas (PHEOs/PGLs) are rare in children with only a few SDHB mutation-related cases. Previous studies on children were conducted in small cohorts. This large set of pediatric patients provides robust data in the evaluation of clinical outcomes.