Open AccessA retrospective case control study identifies peripheral blood mononuclear cell albumin RNA expression as a biomarker for non-alcoholic fatty liver disease
Author(s) -
Xin Chu,
Kelsey Karasinski,
Sean Donellan,
Scott Kaniper,
G. Craig Wood,
WeiXing Shi,
Michael A. Edwards,
Rohit Soans,
Christopher D. Still,
Glenn S. Gerhard
Publication year - 2019
Publication title -
langenbeck's archives of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.235
H-Index - 80
eISSN - 1435-2451
pISSN - 1435-2443
DOI - 10.1007/s00423-019-01848-0
Subject(s) - adipose tissue , fatty liver , peripheral blood mononuclear cell , medicine , albumin , pathology , fibrosis , histology , inflammation , steatosis , liver biopsy , biomarker , liver disease , biopsy , biology , disease , biochemistry , in vitro
Non-alcoholic fatty liver disease (NAFLD) improves after bariatric surgery. The aim of this study was to determine whether peripheral blood mononuclear cell albumin gene expression was related to NAFLD and whether albumin (ALB) and alpha fetoprotein (AFP) expression could be detected in whole blood and visceral adipose tissue.