Normalized grip strength is a sensitive outcome measure through all stages of Duchenne muscular dystrophy | Zendy

JeanYves Hogrel | Zendy; V. Decostre | Zendy; Isabelle Ledoux | Zendy; Marie De Antonio | Zendy; E. Niks | Zendy; Imelda J. M. de Groot | Zendy; Volker Straub | Zendy; Francesco Muntoni | Zendy; Valeria Ricotti | Zendy; Thomas Voit | Zendy; A. Seferian | Zendy; Teresa Gidaro | Zendy; Laurent Servais | Zendy

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Normalized grip strength is a sensitive outcome measure through all stages of Duchenne muscular dystrophy

Author(s) -

JeanYves Hogrel,

V. Decostre,

Isabelle Ledoux,

Marie De Antonio,

E. Niks,

Imelda J. M. de Groot,

Volker Straub,

Francesco Muntoni,

Valeria Ricotti,

Thomas Voit,

A. Seferian,

Teresa Gidaro,

Laurent Servais

Publication year - 2020

Publication title -

journal of neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 136

eISSN - 1432-1459

pISSN - 0340-5354

DOI - 10.1007/s00415-020-09800-9

Subject(s) - grip strength , medicine , duchenne muscular dystrophy , ambulatory , cohort , physical therapy , physical medicine and rehabilitation , surgery

The main aim was to explore the changes in hand-grip strength in patients with Duchenne muscular dystrophy (DMD) aged 5-29 years. Secondary aims were to test the effect of mutation, ambulatory status and glucocorticoid use on grip strength and its changes over time and to compute the number of subjects needed for a clinical trial to stabilize grip strength.

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