Open AccessImaging respiratory muscle quality and function in Duchenne muscular dystrophy
Author(s) -
Alison M. Barnard,
Donovan J. Lott,
Abhinandan Batra,
William Triplett,
Sean C. Forbes,
Samuel L. Riehl,
Rebecca J. Willcocks,
Barbara K. Smith,
Krista Vandenborne,
Glenn A. Walter
Publication year - 2019
Publication title -
journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 136
eISSN - 1432-1459
pISSN - 0340-5354
DOI - 10.1007/s00415-019-09481-z
Subject(s) - duchenne muscular dystrophy , magnetic resonance imaging , medicine , muscles of respiration , respiratory system , diaphragm (acoustics) , anatomy , pulmonary function testing , muscular dystrophy , thorax (insect anatomy) , neuroradiology , cardiology , radiology , neurology , psychiatry , acoustics , loudspeaker , physics
Duchenne muscular dystrophy (DMD) is characterized by damage to muscles including the muscles involved in respiration. Dystrophic muscles become weak and infiltrated with fatty tissue, resulting in progressive respiratory impairment. The objective of this study was to assess respiratory muscle quality and function in DMD using magnetic resonance imaging and to determine the relationship to clinical respiratory function.