Open AccessSurgery associated with increased survival compared to radiation in clinically localized Gleason 9–10 prostate cancer: a SEER analysis
Author(s) -
Amy Nemirovsky,
Hubert Huang,
Gulam Muhammed Al Kibria,
Michael J. Naslund,
Mohummad Minhaj Siddiqui
Publication year - 2020
Publication title -
world journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 83
eISSN - 1433-8726
pISSN - 0724-4983
DOI - 10.1007/s00345-020-03215-x
Subject(s) - medicine , prostate cancer , brachytherapy , external beam radiotherapy , radiation therapy , urology , nephrology , prostate , oncology , epidemiology , surgery , cancer
Men with Gleason score 9-10 prostate cancer have worse outcomes compared to those with Gleason 8 disease. Upfront treatments remain controversial for these patients. Using the Surveillance, Epidemiology, and End Results (SEER) database, we evaluated the impact of initial treatment with external beam radiation therapy (EBRT), external beam radiation therapy with brachytherapy (EBRT + BT), or surgery on prostate cancer-specific mortality (PCSM) and overall mortality (OM) in Gleason 9-10 disease.