Open AccessAccuracy of common proton density fat fraction thresholds for magnitude- and complex-based chemical shift-encoded MRI for assessing hepatic steatosis in patients with obesity
Author(s) -
Guilherme Moura Cunha,
Tydus Thai,
Gavin Hamilton,
Yesenia Covarrubias,
Alexandra Schlein,
Michael S. Middleton,
Curtis N. Wiens,
A. McMillan,
Rashmi Agni,
Luke M. Funk,
Guilherme M. Campos,
Santiago Horgan,
Garth Jacobson,
Tanya Wolfson,
Anthony Gamst,
Jeffrey B. Schwimmer,
Scott B. Reeder,
Claude B. Sirlin
Publication year - 2019
Publication title -
abdominal radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.824
H-Index - 74
eISSN - 2366-004X
pISSN - 2366-0058
DOI - 10.1007/s00261-019-02350-3
Subject(s) - steatosis , medicine , hepatology , mcnemar's test , receiver operating characteristic , nuclear medicine , magnetic resonance imaging , radiology , gastroenterology , statistics , mathematics
MRI proton density fat fraction (PDFF) can be calculated using magnitude (MRI-M) or complex (MRI-C) MRI data. The purpose of this study was to identify, assess, and compare the accuracy of common PDFF thresholds for MRI-M and MRI-C for assessing hepatic steatosis in patients with obesity, using histology as reference.