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Mucinous rectal cancer: concepts and imaging challenges
Author(s) -
Natally Horvat,
Thomas A. Hope,
Perry J. Pickhardt,
Iva Petkovska
Publication year - 2019
Publication title -
abdominal radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.824
H-Index - 74
eISSN - 2366-004X
pISSN - 2366-0058
DOI - 10.1007/s00261-019-02019-x
Subject(s) - medicine , adenocarcinoma , positron emission tomography , hepatology , colorectal cancer , radiology , neoadjuvant therapy , cancer , mucinous carcinoma , breast cancer
Rectal adenocarcinoma with mucinous components is an uncommon type of rectal cancer with two distinct histologic subtypes: mucinous adenocarcinoma and signet-ring cell carcinoma. Mucin can also be identified as pattern of response after neoadjuvant treatment. On imaging modalities, mucin typically demonstrates high signal intensity on T2-weighted images, low attenuation on computed tomography, and may be negative on 18-fluorodeoxyglucose positron emission tomography. After neoadjuvant CRT, cellular and acellular mucin share similar imaging features, and differentiating them is currently the main challenge faced by radiologists. Radiologists should be aware of pros, cons, and limitations of each imaging modality in the primary staging and restaging to avoid misinterpretation of the radiological findings.

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