ImmunoPET/NIRF/Cerenkov multimodality imaging of ICAM-1 in pancreatic ductal adenocarcinoma | Zendy

Miao Li | Zendy; Weijun Wei | Zendy; Todd E. Barnhart | Zendy; Dawei Jiang | Zendy; Tianye Cao | Zendy; Kevin Fan | Zendy; Jonathan W. Engle | Zendy; Jianjun Liu | Zendy; Weiyu Chen | Zendy; Weibo Cai | Zendy

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ImmunoPET/NIRF/Cerenkov multimodality imaging of ICAM-1 in pancreatic ductal adenocarcinoma

Author(s) -

Miao Li,

Weijun Wei,

Todd E. Barnhart,

Dawei Jiang,

Tianye Cao,

Kevin Fan,

Jonathan W. Engle,

Jianjun Liu,

Weiyu Chen,

Weibo Cai

Publication year - 2021

Publication title -

european journal of nuclear medicine and molecular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.313

H-Index - 163

eISSN - 1619-7089

pISSN - 1619-7070

DOI - 10.1007/s00259-021-05216-3

Subject(s) - biodistribution , flow cytometry , positron emission tomography , in vivo , pathology , cancer research , medicine , monoclonal antibody , icam 1 , adenocarcinoma , molecular imaging , nuclear medicine , chemistry , cancer , cell adhesion molecule , antibody , immunology , biology , microbiology and biotechnology

We dual-labeled an intercellular adhesion molecule-1 (ICAM-1) monoclonal antibody (mAb) and evaluated its effectiveness for lesion detection and surgical navigation in pancreatic ductal adenocarcinoma (PDAC) via multiple noninvasive imaging approaches, including positron emission tomography (PET), near-infrared fluorescence (NIRF), and Cerenkov luminescence imaging (CLI).

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