Open AccessIndication of retrograde tau spreading along Braak stages and functional connectivity pathways
Author(s) -
Joseph Seemiller,
Gérard N. Bischof,
Merle Hoenig,
Masoud Tahmasian,
Thilo van Eimeren,
Alexander Drzezga
Publication year - 2021
Publication title -
european journal of nuclear medicine and molecular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.313
H-Index - 163
eISSN - 1619-7089
pISSN - 1619-7070
DOI - 10.1007/s00259-020-05183-1
Subject(s) - neuroscience , tau pathology , pathological , neurodegeneration , neuroimaging , voxel , tauopathy , pathology , alzheimer's disease neuroimaging initiative , disease , psychology , alzheimer's disease , medicine , radiology
Tau pathology progression in Alzheimer's disease (AD) is explained through the network degeneration hypothesis and the neuropathological Braak stages; however, the compatibility of these models remains unclear.