First-in-human evaluation of [11C]PS13, a novel PET radioligand, to quantify cyclooxygenase-1 in the brain | Zendy

Min-Jeong Kim | Zendy; JaeHoon Lee | Zendy; Fernanda Juarez Anaya | Zendy; Jinsoo Hong | Zendy; William H. Miller | Zendy; Sanjay Telu | Zendy; Prachi Singh | Zendy; Michelle Cortes | Zendy; Katharine Henry | Zendy; George Tye | Zendy; Michael P. Frankland | Zendy; Jose A. Montero Santamaria | Zendy; Jeih-San Liow | Zendy; Sami S. Zoghbi | Zendy; Masahiro Fujita | Zendy; Victor W. Pike | Zendy; Robert B. Innis | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

First-in-human evaluation of [11C]PS13, a novel PET radioligand, to quantify cyclooxygenase-1 in the brain

Author(s) -

Min-Jeong Kim,

JaeHoon Lee,

Fernanda Juarez Anaya,

Jinsoo Hong,

William H. Miller,

Sanjay Telu,

Prachi Singh,

Michelle Cortes,

Katharine Henry,

George Tye,

Michael P. Frankland,

Jose A. Montero Santamaria,

Jeih-San Liow,

Sami S. Zoghbi,

Masahiro Fujita,

Victor W. Pike,

Robert B. Innis

Publication year - 2020

Publication title -

european journal of nuclear medicine and molecular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.313

H-Index - 163

eISSN - 1619-7089

pISSN - 1619-7070

DOI - 10.1007/s00259-020-04855-2

Subject(s) - radioligand , cyclooxygenase , medicine , human brain , radioligand assay , pharmacology , nuclear medicine , chemistry , receptor , biochemistry , psychiatry , enzyme

This study assessed whether the newly developed PET radioligand [ 11 C]PS13, which has shown excellent in vivo selectivity in previous animal studies, could be used to quantify constitutive levels of cyclooxygenase-1 (COX-1) in healthy human brain.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research