Open AccessAssociation of aortic vascular uptake of 18FDG by PET/CT and aortic wall thickness by MRI in psoriasis: a prospective observational study
Author(s) -
Jacob Groenendyk,
Parag Shukla,
Amit Dey,
Youssef Elnabawi,
Milena Aksentijevich,
Harry Choi,
Leonard Genovese,
Charlotte Harrington,
Balaji Natarajan,
Aditya Goyal,
Aarthi Reddy,
Justin Rodante,
Mohammad Tarek Kabbany,
Ahmed Sadek,
Mina Al Najafi,
Martin P. Playford,
Aditya Joshi,
Mark A. Ahlman,
Joel M. Gelfand,
David A. Bluemke,
Nehal N. Mehta
Publication year - 2019
Publication title -
european journal of nuclear medicine and molecular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.313
H-Index - 163
eISSN - 1619-7089
pISSN - 1619-7070
DOI - 10.1007/s00259-019-04454-w
Subject(s) - medicine , psoriasis , aorta , cardiology , subclinical infection , prospective cohort study , radiology , dermatology
The contribution of inflammation to the incidence of cardiovascular disease (CVD) has been increasingly recognized in recent years. We investigated the relationship of aortic vascular uptake of 18F-FDG by PET/CT and aortic wall thickness (AWT) by MRI in psoriasis, a chronic inflammatory disease with increased incidence of CVD. One hundred sixty-five patients with plaque psoriasis participated in an ongoing longitudinal cohort study. Subclinical atherosclerosis was assessed as aortic uptake of 18F-FDG by PET/CT reported as target-to-background ratio (TBR) and AWT by MRI reported as maximal thickness.