Noradrenaline transporter availability on [11C]MRB PET predicts weight loss success in highly obese adults
Author(s) -
Franziska Vettermann,
Michael Rullmann,
Georg Becker,
Julia Luthardt,
Franziska Zientek,
Marianne Patt,
Philipp Meyer,
Anke McLeod,
Matthias Brendel,
Matthias Blüher,
Michael Stümvoll,
Anja Hilbert,
YuShin Ding,
Osama Sabri,
Swen Hesse
Publication year - 2018
Publication title -
european journal of nuclear medicine and molecular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.313
H-Index - 163
eISSN - 1619-7089
pISSN - 1619-7070
DOI - 10.1007/s00259-018-4002-7
Subject(s) - medicine , body mass index , weight loss , insula , prefrontal cortex , endocrinology , appetite , obesity , psychology , neuroscience , psychiatry , cognition
Although the mechanisms by which the central noradrenaline (NA) system influences appetite and controls energy balance are quite well understood, its relationship to changes in body weight remains largely unknown. The main goal of this study was to further clarify whether the brain NA system is a stable trait or whether it can be altered by dietary intervention.
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