Open AccessMR imaging phenotype correlates with extent of genome-wide copy number abundance in IDH mutant gliomas
Author(s) -
ChhiChong Wu,
Rajan Jain,
Lucidio Neto,
Seema Patel,
Laila Poisson,
Jonathan Serrano,
Victor Ng,
Sohil H. Patel,
Dimitris G. Placantonakis,
David Zagzag,
John G. Golfinos,
S. Andrew,
Matija Snuderl
Publication year - 2019
Publication title -
neuroradiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.811
H-Index - 94
eISSN - 1432-1920
pISSN - 0028-3940
DOI - 10.1007/s00234-019-02219-8
Subject(s) - copy number variation , astrocytoma , cdkn2b , glioma , pathology , medicine , biology , cancer research , genetics , cdkn2a , gene , genome
There is variability in survival within IDH mutant gliomas determined by chromosomal events. Copy number variation (CNV) abundance associated with survival in low-grade and IDH mutant astrocytoma has been reported. Our purpose was to correlate the extent of genome-wide CNV abundance in IDH mutant astrocytomas with MRI features.